Протокол разведения по MVD, Болезнь митрального клапана Опции

[Admin.]

Финская схема допуска в разведение по сердцу:

The Finnish CKCS club adds to that the recommendation that if the cavalier is under 3 years old, the dog must have no MVD murmur and either: (a) the dog's parents were MVD-clear at age 5 years, or ( the dog is MVD-clear by echocardiograph. A revision of this breeding recommendation is being considered that would stiffen the protocol:

• If the cavalier is between 3 and 5 years old, the dog must have no MVD murmur and the dog's parents were MVD-clear at age 5 years.
• If the cavalier is between 2 and 3 years old, the dog must have no MVD murmur and the dog's parents were MVD-clear at age 6 years.
• If either of the male cavalier's parents had an MVD-murmur before age 5 years old, the dog cannot be bred before age 5 years old and MVD-clear.
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Британская схема (май 2018). Она не настолько строгая, как Финская.

May 2018: UK Kennel Club announces new MVD breeding scheme for cavaliers. UK Kennel Club. In a May 2018 press release, the The UK Kennel Club and the UK Veterinary Cardiovascular Society announced on May 21, 2018 that they have developed a new MVD breeding scheme for cavalier King Charles spaniels. Application of the breed scheme will begin with a trial of 100 dogs, and later this year, it will be available to all cavalier breeders and owners.

The new testing scheme is:

1. FIRST EXAMINATION: Beginning between age 18 months to 2 years, breeding stock cavaliers should be examined by a cardiologist by stethoscope (auscultation) to determine if they have a mitral valve murmur, and by echocardiograph (Doppler), to determine if they have mitral valve prolapse and to confirm whether the murmur is in fact from the mitral valve.

2. SUBSEQUENT EXAMINATIONS: If the dogs are still being used for breeding, re-assessments should be performed at ages 4 years and 6 years.

3. MURMURS: Mitral valve murmurs will be graded from 0 to 6, with 0 indicating no murmur and 6 indicating the most severe murmur.

4. PROLAPSE: Mitral valve prolapse (MVP) will be graded 0 to 3, as follows:

• 0 – none
• 1 – mild
• 2 – moderate
• 3 – severe

• GREEN: Cavaliers with Grade 0 or 1 murmur and Grade 0 or 1 MVP are be considered to be at the lowest risk of developing congestive heart failure (CHF) from MVD, and therefore represent the lowest breeding risk.

• AMBER: Cavaliers with a Grade 2 murmur OR Grade 2 MVP (but not both) have a greater risk of developing CHF or passing the condition on to offspring.

The UK Kennel Club advises that, to reduce the genetic risk of MVD in offspring, only Amber dogs otherwise in excellent health, and with good results from other screening schemes, may be used cautiously for breeding, with particular care to use mates which have been categorized as Green under the scheme, preferably at 4 years of age or older.

Dogs categorized as Amber at ages 4 or 6 years (or older) are considered to represent less of a risk than those categorized as Amber at the first examination at 18 months to 2 years.

• RED: Cavaliers with both a Grade 2 murmur AND a Grade 2 MVP, or a Grade 3 murmur or above, or a Grade 3 MVP, or otherwise have significant heart disease, are advised not to be used for breeding, as they are considered to represent the greatest breeding risk.

6. RECORD OF EXAMINATION: The detailed results of the examinations, including the Doppler images, will be recorded on an electronic form, which will be distributed to the dog’s owner, the Kennel Club, and the examining cardiologist. In the Comment section of the form, the cardiologist may state that the dog is ”heart recommended or not recommended for breeding”. The Kennel Club will add the grades to the dog’s record. At the time of the assessment, the cardiologist will stamp the dog’s registration certificate if the dog’s owner requests.

[Admin.]

Датский протокол разведения доказал свою эффективность, сократив на 71% риск заболевания сердца.
Собаки по нему тестируются один раз в возрасте 1,5 лет или старше, что даёт допуск в разведение до 4 лет. Затем в возрасте старше 4 лет тестирование повторяют, и потом пожизненный допуск для сук, а для кобелей ещё одно тестирование старше 6 лет. Из разведения исключаются собаки с 3 и более тяжелой стадией шумов и 3 и более стадии пролапса. А также общая комбинация (шумы+пролапс) не должны превышать 3. До 2007 года допускали в разведение собак с 3 стадией пролапса, если шумы были не больше 1 ст.

Danish cavaliers show 71% reduced risk of MVD under a mandatory breeding protocol.
Denmark's MVD breeding guidelines are:

1. Dogs examined at 1½ years of age or older were approved for breeding until 4 years of age if cardiac health criteria were fulfilled.

2. To continue breeding after 4 years of age, the dogs had to be reexamined. In January 2007, an additional restriction was added, requiring a reexamination after 6 years of age for male dogs.

3. At all examination time points, dogs were excluded from breeding if they had MVP (mitral valve prolapse by echocardiograph) grade 3 or a mitral regurgitation murmur grade 3 or higher.

4. The degree of MVP was assessed as:
• Grade 0 (≤1.5 mm as the sum of the maximum protrusion of the cranial, caudal and coaption point of the mitral valve according to annulus plane)
• Grade 1 (>1.5 and ≤4.5 mm)
• Grade 2 (>4.5 and ≤7.5 mm)
• Grade 3 (>7.5 mm).

5. • Dogs with grade 2 murmurs were excluded if they had MVP grades 2 or 3;
• Mitral regurgitation murmur of 1 at a maximum combined with a MVP grade 2 at a maximum; or
• A grade 2 murmur combined with a degree of MVP not above grade 1.
• Before 2007, dogs with a grade 3 MVP were approved if they had a murmur grade not above 1.